Corneal abrasion is a superficial disruption of the corneal surface. Which treatment component should not be prescribed for home use due to impairment of healing?

• A. Ciprofloxacin ear drops
• B. Polymyxin B, Neomycin, and Hydrocortisone
• C. Amoxicillin
• D. Erythromycin ointment

Answer: (B)

Healing of a corneal abrasion hinges on rapid re-epithelialization of the surface. A corticosteroid in a home treatment delays this healing process by reducing epithelial cell migration and suppressing the local immune response, which can also mask worsening infection and increase the risk of complications like corneal thinning or melt. Therefore, any regimen that includes a corticosteroid should not be used at home right after a corneal abrasion. The component that contains a steroid is the one to avoid. The other options are antibiotics without a steroid and are not known to impair epithelial healing in the same way, so they are more suitable for home management to prevent or treat infection.